Ontology highlight
ABSTRACT:
SUBMITTER: Kapur NK
PROVIDER: S-EPMC6259487 | biostudies-literature | 2018
REPOSITORIES: biostudies-literature
Kapur Navin K NK Annamalai Shiva S Reyelt Lara L Karmiy Samuel J SJ Razavi Allen A AA Foroutanjazi Sina S Chennojwala Aditya A Ishikawa Kiyotake K
F1000Research 20181127
Heart failure is a major cause of global morbidity and mortality. Acute myocardial infarction (AMI) is a primary cause of heart failure due in large part to residual myocardial damage despite timely reperfusion therapy. Since the 1970's, multiple preclinical laboratories have tested whether reducing myocardial oxygen demand with a mechanical support pump can reduce infarct size in AMI. In the past decade, this hypothesis has been studied using contemporary circulatory support pumps. We will revi ...[more]