Ontology highlight
ABSTRACT:
SUBMITTER: Godoy PM
PROVIDER: S-EPMC6261476 | biostudies-literature | 2018 Oct
REPOSITORIES: biostudies-literature
Godoy Paula M PM Bhakta Nirav R NR Barczak Andrea J AJ Cakmak Hakan H Fisher Susan S MacKenzie Tippi C TC Patel Tushar T Price Richard W RW Smith James F JF Woodruff Prescott G PG Erle David J DJ
Cell reports 20181001 5
Extracellular microRNAs (miRNAs) and other small RNAs are implicated in cellular communication and may be useful as disease biomarkers. We systematically compared small RNAs in 12 human biofluid types using RNA sequencing (RNA-seq). miRNAs and tRNA-derived RNAs (tDRs) accounted for the majority of mapped reads in all biofluids, but the ratio of miRNA to tDR reads varied from 72 in plasma to 0.004 in bile. miRNA levels were highly correlated across all biofluids, but levels of some miRNAs differe ...[more]