Ontology highlight
ABSTRACT:
SUBMITTER: Srinivasan S
PROVIDER: S-EPMC6557167 | biostudies-literature | 2019 Apr
REPOSITORIES: biostudies-literature
Srinivasan Srimeenakshi S Yeri Ashish A Cheah Pike See PS Chung Allen A Danielson Kirsty K De Hoff Peter P Filant Justyna J Laurent Clara D CD Laurent Lucie D LD Magee Rogan R Moeller Courtney C Murthy Venkatesh L VL Nejad Parham P Paul Anu A Rigoutsos Isidore I Rodosthenous Rodosthenis R Shah Ravi V RV Simonson Bridget B To Cuong C Wong David D Yan Irene K IK Zhang Xuan X Balaj Leonora L Breakefield Xandra O XO Daaboul George G Gandhi Roopali R Lapidus Jodi J Londin Eric E Patel Tushar T Raffai Robert L RL Sood Anil K AK Alexander Roger P RP Das Saumya S Laurent Louise C LC
Cell 20190401 2
Poor reproducibility within and across studies arising from lack of knowledge regarding the performance of extracellular RNA (exRNA) isolation methods has hindered progress in the exRNA field. A systematic comparison of 10 exRNA isolation methods across 5 biofluids revealed marked differences in the complexity and reproducibility of the resulting small RNA-seq profiles. The relative efficiency with which each method accessed different exRNA carrier subclasses was determined by estimating the pro ...[more]