Ontology highlight
ABSTRACT:
SUBMITTER: Pallares V
PROVIDER: S-EPMC6265715 | biostudies-literature | 2018 Nov
REPOSITORIES: biostudies-literature
Pallarès Victor V Hoyos Montserrat M Chillón M Carmen MC Barragán Eva E Prieto Conde M Isabel MI Llop Marta M Falgàs Aïda A Céspedes María Virtudes MV Montesinos Pau P Nomdedeu Josep F JF Brunet Salut S Sanz Miguel Ángel MÁ González-Díaz Marcos M Sierra Jorge J Mangues Ramon R Casanova Isolda I
Cancers 20181113 11
In recent years, several attempts have been made to identify novel prognostic markers in patients with intermediate-risk acute myeloid leukemia (IR-AML), to implement risk-adapted strategies. The non-receptor tyrosine kinases are proteins involved in regulation of cell growth, adhesion, migration and apoptosis. They associate with metastatic dissemination in solid tumors and poor prognosis. However, their role in haematological malignancies has been scarcely studied. We hypothesized that <i>PTK2 ...[more]