Effects of Pravastatin in Adriamycin-Induced Nephropathy in Rats.
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SUBMITTER: Mansouri E
PROVIDER: S-EPMC6269566 | biostudies-literature | 2018
REPOSITORIES: biostudies-literature
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Effects of Pravastatin in Adriamycin-Induced Nephropathy in Rats.
Mansouri Esrafil E Assarehzadegan Mohammad-Ali MA Nejad-Dehbashi Fereshteh F Kooti Wesam W
Iranian journal of pharmaceutical research : IJPR 20180101 4
The aim of this study is to evaluate the effects of pravastatin on Adriamycin (ADR)-induced nephropathy and the mechanisms involved. Forty rats were divided into the following 4 groups: control, ADR (15 mg.kg<sup>-1</sup>, IP), ADR plus pravastatin (20 mg.kg<sup>-1</sup> which was started 5 days prior to ADR injection), and ADR plus pravastatin (20 mg.kg<sup>-1</sup> which was started 5 days after ADR injection). On day 20 after ADR injection, the animals were sacrificed. The results showed that ...[more]
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