Ontology highlight
ABSTRACT:
SUBMITTER: Zhao H
PROVIDER: S-EPMC6270060 | biostudies-literature | 2013 Mar
REPOSITORIES: biostudies-literature
Zhao Hanqing H Zhou Minjie M Duan Lifeng L Wang Wei W Zhang Jianjun J Wang Daoquan D Liang Xiaomei X
Molecules (Basel, Switzerland) 20130321 3
In order to develop potential glucosamine-6-phosphate synthase inhibitors and anti-fungal agents, twenty five oleanolic acid oxime esters were synthesized in an efficient way. The structures of the new compounds were confirmed by MS, HRMS, 1H-NMR and 13C-NMR. Preliminary studies based on means of the Elson-Morgan method indicated that many compounds exhibited some inhibitory activity of glucosamine-6-phosphate synthase (GlmS), and the original fungicidal activities results showed that some of th ...[more]