Ontology highlight
ABSTRACT:
SUBMITTER: Saudi M
PROVIDER: S-EPMC6270414 | biostudies-literature | 2013 Jul
REPOSITORIES: biostudies-literature
Saudi Milind M van Aerschot Arthur A
Molecules (Basel, Switzerland) 20130718 7
Benzhydryl protection of primary and secondary alcohols has been reported previously via reaction with metal alcoholates. Our aim was to find generally useful and very mild conditions for the alcoholic protection and deprotection of nucleosides with the diphenylmethyl group. This was accomplished for some pyrimidine nucleosides using PdCl₂ as the transition metal catalyst, and with optimization yields of 70-90% have been achieved. A lack of solubility of other nucleosides hampers its more genera ...[more]