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'One-pot' synthesis of dihydrobenzo[4,5][1,3]oxazino[2,3-a] isoquinolines via a silver(I)-catalyzed cascade approach.

ABSTRACT: An efficient approach for the synthesis of biologically interesting fused tetracyclic isoquinolines in high yields and with a broad substrate scope has been developed. The strategy features an AgNO(3) catalyzed 'one-pot' cascade process involving formation of two new C-N bonds and one new C-O bond.

SUBMITTER: Jiang B

PROVIDER: S-EPMC6270568 | biostudies-literature | 2013 Jan

REPOSITORIES: biostudies-literature

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'One-pot' synthesis of dihydrobenzo[4,5][1,3]oxazino[2,3-a] isoquinolines via a silver(I)-catalyzed cascade approach.

Jiang Baifeng B Zhou Yu Y Kong Qingya Q Jiang Hualiang H Liu Hong H Li Jian J

Molecules (Basel, Switzerland) 20130111 1

An efficient approach for the synthesis of biologically interesting fused tetracyclic isoquinolines in high yields and with a broad substrate scope has been developed. The strategy features an AgNO(3) catalyzed 'one-pot' cascade process involving formation of two new C-N bonds and one new C-O bond. ...[more]

PMID: 23344195

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