Ontology highlight
ABSTRACT:
SUBMITTER: Bai XG
PROVIDER: S-EPMC6271338 | biostudies-literature | 2014 Oct
REPOSITORIES: biostudies-literature
Bai Xiao-Guang XG Xu Chang-Liang CL Zhao Shuang-Shuang SS He Hong-Wei HW Wang Yu-Cheng YC Wang Ju-Xian JX
Molecules (Basel, Switzerland) 20141028 11
A series of chalcones a1-20 bearing a 4-OMe groups on the A-ring were initially synthesized and their anticancer activities towards HepG2 cells evaluated. Subsequently, a series of chalcones b1-42 bearing methoxy groups at the 2' and 6'-positions of the B-ring were synthesized and their anticancer activities towards five human cancer cell lines (HepG2, HeLa, MCF-7, A549 and SW1990) and two non-tumoral human cell lines evaluated. The results showed that six compounds (b6, b8, b11, b16, b18, b22, ...[more]