Ontology highlight
ABSTRACT:
SUBMITTER: Liu YJ
PROVIDER: S-EPMC6271793 | biostudies-literature | 2014 Nov
REPOSITORIES: biostudies-literature
Liu Yu-Jia YJ Zhao Yu-Jun YJ Zhang Meng M Su Ping P Wang Xiu-Juan XJ Zhang Xia-Nan XN Gao Wei W Huang Lu-Qi LQ
Molecules (Basel, Switzerland) 20141127 12
Tripterygium wilfordii is a traditional Chinese medical plant used to treat rheumatoid arthritis and cancer. The main bioactive compounds of the plant are diterpenoids and triterpenoids. 3-Hydroxy-3-methylglutaryl-CoA synthase (HMGS) catalyses the reaction of acetoacetyl-CoA to 3-hydroxy-3-methylglutaryl-CoA, which is the first committed enzyme in the mevalonate (MVA) pathway. The sequence information of HMGS in Tripterygium wilfordii is a basic resource necessary for studying the terpenoids in ...[more]