Unknown

Dataset Information

0

An alkaloid and a steroid from the endophytic fungus Aspergillus fumigatus.


ABSTRACT: Two new compounds, fumitremorgin 12-methoxy-13-[5'-hydroxy-2'-(1''-hydroxy-3''-methoxy-5''-methylbenzoyl)-3'-methoxy]benzoic acid methyl ester (fumitremorgin D, 1) and 4,8,10,14-tetramethyl-6-acetoxy-14-[16-acetoxy-19-(20,21-dimethyl)-18-ene]-phenanthrene-1-ene-3,7-dione (2) were isolated from the cultured endophytic isolated fungus Aspergillus fumigatus, together with fourteen known compounds. Their structures were elucidated by 1-D and 2-D NMR analyses. The cytotoxicity profile of the compound against the human hepatocellular carcinoma cell line HepG2 was evaluated by MTT antiproliferative assays.

SUBMITTER: Liang Z 

PROVIDER: S-EPMC6272270 | biostudies-literature | 2015 Jan

REPOSITORIES: biostudies-literature

altmetric image

Publications

An alkaloid and a steroid from the endophytic fungus Aspergillus fumigatus.

Liang Zizhen Z   Zhang Tiantian T   Zhang Xiaoqian X   Zhang Jia J   Zhao Changqi C  

Molecules (Basel, Switzerland) 20150114 1


Two new compounds, fumitremorgin 12-methoxy-13-[5'-hydroxy-2'-(1''-hydroxy-3''-methoxy-5''-methylbenzoyl)-3'-methoxy]benzoic acid methyl ester (fumitremorgin D, 1) and 4,8,10,14-tetramethyl-6-acetoxy-14-[16-acetoxy-19-(20,21-dimethyl)-18-ene]-phenanthrene-1-ene-3,7-dione (2) were isolated from the cultured endophytic isolated fungus Aspergillus fumigatus, together with fourteen known compounds. Their structures were elucidated by 1-D and 2-D NMR analyses. The cytotoxicity profile of the compound  ...[more]

Similar Datasets

| S-EPMC6100219 | biostudies-literature
| S-EPMC6272661 | biostudies-literature
| S-EPMC5315648 | biostudies-literature
| S-EPMC2289846 | biostudies-literature
| S-EPMC1865896 | biostudies-literature
| S-EPMC4432157 | biostudies-literature
| S-EPMC1151871 | biostudies-literature
| S-EPMC9054444 | biostudies-literature
| S-EPMC7401266 | biostudies-literature
| S-EPMC6273775 | biostudies-literature