Ontology highlight
ABSTRACT:
SUBMITTER: Sanchez-Sanchez L
PROVIDER: S-EPMC6273349 | biostudies-literature | 2016 Nov
REPOSITORIES: biostudies-literature
Sánchez-Sánchez Luis L Hernández-Linares María Guadalupe MG Escobar María L ML López-Muñoz Hugo H Zenteno Edgar E Fernández-Herrera María A MA Guerrero-Luna Gabriel G Carrasco-Carballo Alan A Sandoval-Ramírez Jesús J
Molecules (Basel, Switzerland) 20161114 11
Steroidal sapogenins have shown antiproliferative effects against several tumor cell lines; and their effects on human cancer cells are currently under study. Changes in the functionality on the steroidal structure make it possible to modify the biological activity of compounds. Herein, we report the synthesis and in vitro antitumor activity of two steroidal oxime compounds on cervical cancer cells. These derivatives were synthesized from the steroidal sapogenin diosgenin in good yields. The in ...[more]