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Casbane Diterpenes from Red Sea Coral Sinularia polydactyla.

ABSTRACT: The soft coral genus Sinularia is a rich source of bioactive metabolites containing a diverse array of chemical structures. A solvent extract of Sinularia polydactyla resulted in the isolation of three new casbane diterpenes: sinularcasbane M (1), sinularcasbane N (2) and sinularcasbane O (3); in addition, known metabolites (4-5) were isolated. Compounds were elucidated on the basis of spectroscopic analyses; the absolute configuration was confirmed by X-ray analysis.

SUBMITTER: Hegazy ME

PROVIDER: S-EPMC6274415 | biostudies-literature | 2016 Mar

REPOSITORIES: biostudies-literature

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Casbane Diterpenes from Red Sea Coral Sinularia polydactyla.

Hegazy Mohamed-Elamir F ME Mohamed Tarik A TA Elshamy Abdelsamed I AI Al-Hammady Montaser A MA Ohta Shinji S Paré Paul W PW

Molecules (Basel, Switzerland) 20160303 3

The soft coral genus Sinularia is a rich source of bioactive metabolites containing a diverse array of chemical structures. A solvent extract of Sinularia polydactyla resulted in the isolation of three new casbane diterpenes: sinularcasbane M (1), sinularcasbane N (2) and sinularcasbane O (3); in addition, known metabolites (4-5) were isolated. Compounds were elucidated on the basis of spectroscopic analyses; the absolute configuration was confirmed by X-ray analysis. ...[more]

PMID: 26950110

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