Ontology highlight
ABSTRACT:
SUBMITTER: Plan Sangnier A
PROVIDER: S-EPMC6278761 | biostudies-literature | 2018
REPOSITORIES: biostudies-literature
Plan Sangnier Anouchka A Aufaure Romain R Motte Laurence L Wilhelm Claire C Guenin Erwann E Lalatonne Yoann Y
Beilstein journal of nanotechnology 20181127
A gold therapeutic nanoplatform with the same molecule used as reductant, coating and therapeutic agent has been developed in a one-pot, one-phase process using alendronate, a drug from the bisphosphonate family known for its antitumor effects. In addition, the core made of gold nanoparticles (NPs) brings thermal functionalities under irradiation within the first biological window (650-900 nm). The Au@alendronate nanoplatform thus provided a combined antitumor activity through drug delivery and ...[more]