Ontology highlight
ABSTRACT:
SUBMITTER: Paramsothy S
PROVIDER: S-EPMC6279599 | biostudies-literature | 2018 Nov
REPOSITORIES: biostudies-literature
Paramsothy Sudarshan S Rosenstein Adam K AK Mehandru Saurabh S Colombel Jean-Frederic JF
Mucosal immunology 20180615 6
The emergence of biologic therapies is arguably the greatest therapeutic advance in the care of inflammatory bowel disease (IBD) to date, allowing directed treatments targeted at highly specific molecules shown to play critical roles in disease pathogenesis, with advantages in potency and selectivity. Furthermore, a large number of new biologic and small-molecule therapies in IBD targeting a variety of pathways are at various stages of development that should soon lead to a dramatic expansion in ...[more]