Ontology highlight
ABSTRACT:
SUBMITTER: Niedzielska M
PROVIDER: S-EPMC6281418 | biostudies-literature | 2018 Nov
REPOSITORIES: biostudies-literature
Niedzielska Magdalena M Israelsson Elisabeth E Angermann Bastian B Sidders Benjamin S BS Clausen Maryam M Catley Matthew M Malhotra Rajneesh R Dumont Céline C
Oncotarget 20181116 90
As we learn more about how immune responses occur <i>in situ</i>, it is becoming clear that each organ/tissue is characterized with its own anatomy and microenvironment which may affect and even determine the outcome of the immune responses. With emerging data from animal studies showing that regulatory T cells infiltrating non-lymphoid tissues exhibit unique phenotypes and transcriptional signatures and display functions beyond their well-established suppressive roles, there is an urgent need t ...[more]