Ontology highlight
ABSTRACT:
SUBMITTER: Nguyen LTH
PROVIDER: S-EPMC6282138 | biostudies-literature | 2018
REPOSITORIES: biostudies-literature
Nguyen Luong T H LTH Muktabar Aristo A Tang Jinkai J Wong Yee Shan YS Thaxton Colby S CS Venkatraman Subbu S SS Ng Kee Woei KW
BioMed research international 20181122
Inflammation plays an important role in all stages of atherosclerosis development. Therefore, the use of anti-inflammatory drugs could reduce the risk of major adverse cardiovascular events due to atherosclerosis. Herein, we explored the capacity of fluocinolone acetonide (FA), a glucocorticoid (GC), in modulating foam cell formation and response. Human THP-1 derived foam cells were produced using 100 <i>μ</i>g/mL oxidized low-density lipoproteins (OxLDL) and fetal bovine serum (1 and 10%). 2D c ...[more]