Impact of a Nonfatal Dengue Episode on Disability-Adjusted Life Years: A Systematic Analysis.

ABSTRACT: As dengue causes about 4,000 symptomatic nonfatal episodes for every dengue death globally, quantitative disability assessments are critical to assess the burden of dengue and the cost-effectiveness of dengue control interventions. This systematic analysis of disability or quality of life lost from a symptomatic nonfatal dengue episode combined a systematic literature review, statistical modeling, and probabilistic sensitivity analyses. We conceptualized a dengue episode as having two phases: acute and persistent symptoms. Our estimates for the acute phase, consisting of onset and recovery periods and defined as the first 20 days (0.054 year), were based on literature review. We searched PubMed, POPLINE, EconLit, Google Scholar, scientific conferences, and other sources, for "dengue" plus

SUBMITTER: Zeng W 

PROVIDER: S-EPMC6283510 | biostudies-literature | 2018 Dec

REPOSITORIES: biostudies-literature