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Aortic dissection albeit negative d-dimers and zero clinical probability - Another facet of medicine's deadly chameleon.


ABSTRACT: Aortic dissection, the rupture of the aorta's intimal and medial layers, leading to the formation of a false lumen, is a relatively common disease with high mortality. So far, while not addressing penetrating aortic ulcer or intramural hematoma, current guidelines take a negative value for d-dimers for a sufficient method to rule out aortic dissection in patients with a low clinical probability, as calculated by the ADD risk score. We present two cases of patients with acute aortic dissection, albeit presenting with a low clinical probability for acute aortic dissection and negative values for d-dimers. .

SUBMITTER: Ruf TF 

PROVIDER: S-EPMC6283770 | biostudies-literature | 2017 Feb

REPOSITORIES: biostudies-literature

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Aortic dissection albeit negative d-dimers and zero clinical probability - Another facet of medicine's deadly chameleon.

Ruf Tobias Friedrich TF   Pfluecke Christian C   Mues Christoph C   Strasser Ruth H RH  

Journal of cardiology cases 20161116 2


Aortic dissection, the rupture of the aorta's intimal and medial layers, leading to the formation of a false lumen, is a relatively common disease with high mortality. So far, while not addressing penetrating aortic ulcer or intramural hematoma, current guidelines take a negative value for d-dimers for a sufficient method to rule out aortic dissection in patients with a low clinical probability, as calculated by the ADD risk score. We present two cases of patients with acute aortic dissection, a  ...[more]

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