Direct screening of plasma circulating microRNAs.
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ABSTRACT:
SUBMITTER: Songia P
PROVIDER: S-EPMC6284556 | biostudies-literature | 2018
REPOSITORIES: biostudies-literature
Publications
Direct screening of plasma circulating microRNAs.
Songia Paola P Chiesa Mattia M Valerio Vincenza V Moschetta Donato D Myasoedova Veronika A VA D'Alessandra Yuri Y Poggio Paolo P
RNA biology 20181009 10
Circulating microRNAs (miRNAs) are considered as reliable candidates for biomarker discovery. RNA-Sequencing has become the most suitable technique to accurately quantify the miRNAome. However, RNA-Sequencing relies on several technical passages before reaching the final-end. HTG EdgeSeq technology, thanks to the abrogation of RNA extraction step, allows productivity enhancement by reducing the number of hands-on steps, the time for sample preparation and, therefore, the costs. We found a strong ...[more]
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