Ontology highlight
ABSTRACT:
SUBMITTER: Karagyozov D
PROVIDER: S-EPMC6287944 | biostudies-literature | 2018 Oct
REPOSITORIES: biostudies-literature
Karagyozov Doycho D Mihovilovic Skanata Mirna M Lesar Amanda A Gershow Marc M
Cell reports 20181001 5
Optical recordings of neural activity in behaving animals can reveal the neural correlates of decision making, but brain motion, which often accompanies behavior, compromises these measurements. Two-photon point-scanning microscopy is especially sensitive to motion artifacts, and two-photon recording of activity has required rigid coupling between the brain and microscope. We developed a two-photon tracking microscope with extremely low-latency (360 μs) feedback implemented in hardware. This mic ...[more]