Ontology highlight
ABSTRACT:
SUBMITTER: Baena-Lopez LA
PROVIDER: S-EPMC6288387 | biostudies-literature | 2018 Dec
REPOSITORIES: biostudies-literature
Baena-Lopez Luis Alberto LA Arthurton Lewis L Bischoff Marcus M Vincent Jean-Paul JP Alexandre Cyrille C McGregor Reuben R
Development (Cambridge, England) 20181204 23
The caspase-mediated regulation of many cellular processes, including apoptosis, justifies the substantial interest in understanding all of the biological features of these enzymes. To complement functional assays, it is crucial to identify caspase-activating cells in live tissues. Our work describes novel initiator caspase reporters that, for the first time, provide direct information concerning the initial steps of the caspase activation cascade in <i>Drosophila</i> tissues. One of our caspase ...[more]