Ontology highlight
ABSTRACT:
SUBMITTER: Jung E
PROVIDER: S-EPMC6290557 | biostudies-literature | 2013 Dec
REPOSITORIES: biostudies-literature
Jung Eunsun E Lee Jung-A JA Shin Seoungwoo S Roh Kyung-Baeg KB Kim Jang-Hyun JH Park Deokhoon D
Molecules (Basel, Switzerland) 20131216 12
Madecassoside (MA), a pentacyclic triterpene isolated from Centella asitica (L.), is used as a therapeutic agent in wound healing and also as an anti-inflammatory and anti-aging agent. However, the involvement of MA in skin-pigmentation has not been reported. This study was conducted to investigate the effects of MA on ultraviolet (UV)-induced melanogenesis and mechanisms in a co-culture system of keratinocytes and melanocytes. MA significantly inhibited UVR-induced melanin synthesis and melanos ...[more]