Ontology highlight
ABSTRACT:
SUBMITTER: Stathias V
PROVIDER: S-EPMC6294341 | biostudies-literature | 2018 Dec
REPOSITORIES: biostudies-literature
Nature communications 20181214 1
Glioblastoma (GBM) is the most common primary adult brain tumor. Despite extensive efforts, the median survival for GBM patients is approximately 14 months. GBM therapy could benefit greatly from patient-specific targeted therapies that maximize treatment efficacy. Here we report a platform termed SynergySeq to identify drug combinations for the treatment of GBM by integrating information from The Cancer Genome Atlas (TCGA) and the Library of Integrated Network-Based Cellular Signatures (LINCS). ...[more]