Dataset Information

Cryfa: a secure encryption tool for genomic data.

ABSTRACT: Summary:The ever-increasing growth of high-throughput sequencing technologies has led to a great acceleration of medical and biological research and discovery. As these platforms advance, the amount of information for diverse genomes increases at unprecedented rates. Confidentiality, integrity and authenticity of such genomic information should be ensured due to its extremely sensitive nature. In this paper, we propose Cryfa, a fast secure encryption tool for genomic data, namely in Fasta, Fastq, VCF, SAM and BAM formats, which is also capable of reducing the storage size of Fasta and Fastq files. Cryfa uses advanced encryption standard (AES) encryption combined with a shuffling mechanism, which leads to a substantial enhancement of the security against low data complexity attacks. Compared to AES Crypt, a general-purpose encryption tool, Cryfa is an industry-oriented tool, which is able to provide confidentiality, integrity and authenticity of data at four times more speed; in addition, it can reduce the file sizes to 1/3. Due to the absence of a method similar to Cryfa, we have simulated its behavior with a combination of encryption and compression tools, for comparison purpose. For instance, our tool is nine times faster than its fastest competitor in Fasta files. Also, Cryfa has a very low memory usage (only a few megabytes), which makes it feasible to run on any computer. Availability and implementation:Source codes and binaries are available, under GPLv3, at https://github.com/pratas/cryfa. Supplementary information:Supplementary data are available at Bioinformatics online.

SUBMITTER: Hosseini M

PROVIDER: S-EPMC6298042 | biostudies-literature | 2019 Jan

REPOSITORIES: biostudies-literature

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Cryfa: a secure encryption tool for genomic data.

Hosseini Morteza M Pratas Diogo D Pinho Armando J AJ

Bioinformatics (Oxford, England) 20190101 1

<h4>Summary</h4>The ever-increasing growth of high-throughput sequencing technologies has led to a great acceleration of medical and biological research and discovery. As these platforms advance, the amount of information for diverse genomes increases at unprecedented rates. Confidentiality, integrity and authenticity of such genomic information should be ensured due to its extremely sensitive nature. In this paper, we propose Cryfa, a fast secure encryption tool for genomic data, namely in Fast ...[more]

PMID: 30020420

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Project description:In response to the vulnerability of image encryption techniques to chosen plaintext attacks, this paper proposes a secure image communication scheme based on two-layer dynamic feedback encryption and discrete wavelet transform (DWT) information hiding. The proposed scheme employs a plaintext correlation and intermediate ciphertext feedback mechanism, and combines chaotic systems, bit-level permutation, bilateral diffusion, and dynamic confusion to ensure the security and confidentiality of transmitted images. Firstly, a dynamically chaotic encryption sequence associated with a secure plaintext hash value is generated and utilized for the first round of bit-level permutation, bilateral diffusion, and dynamic confusion, resulting in an intermediate ciphertext image. Similarly, the characteristic values of the intermediate ciphertext image are used to generate dynamically chaotic encryption sequences associated with them. These sequences are then employed for the second round of bit-level permutation, bilateral diffusion, and dynamic confusion to gain the final ciphertext image. The ciphertext image hidden by DWT also provides efficient encryption, higher level of security and robustness to attacks. This technology offers indiscernible secret data insertion, rendering it challenging for assailants to spot or extract concealed information. By combining the proposed dynamic closed-loop feedback secure image encryption scheme based on the 2D-SLMM chaotic system with DWT-based hiding, a comprehensive and robust image encryption approach can be achieved. According to the results of theoretical research and experimental simulation, our encryption scheme has dynamic encryption effect and reliable security performance. The scheme is highly sensitive to key and plaintext, and can effectively resist various common encryption attacks and maintain good robustness. Therefore, our proposed encryption algorithm is an ideal digital image privacy protection technology, which has a wide range of practical application prospects.

Dataset Information

Cryfa: a secure encryption tool for genomic data.

Publications

Cryfa: a secure encryption tool for genomic data.

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