Ontology highlight
ABSTRACT:
SUBMITTER: Hung SC
PROVIDER: S-EPMC6299401 | biostudies-literature | 2018
REPOSITORIES: biostudies-literature
Hung Sheng-Chun SC Wang Shian-Shiang SS Li Jian-Ri JR Chen Chuan-Shu CS Yang Chun-Kuang CK Chiu Kun-Yuan KY Cheng Chen-Li CL Ou Yen-Chuan YC Ho Hao-Chung HC Yang Shun-Fa SF
International journal of medical sciences 20181122 14
The high mobility group box 1 gene (<i>HMGB1</i>) plays a prominent role in cancer progression, angiogenesis, invasion, and metastasis. This study explored the effect of <i>HMGB1</i> polymorphisms on clinicopathological characteristics of urothelial cell carcinoma (UCC). In total, 1293 participants (431 patients with UCC and 862 healthy controls) were recruited. Four single-nucleotide polymorphisms (SNPs) of <i>HMGB1</i> (rs1412125, rs1360485, rs1045411, and rs2249825) were assessed using TaqMan ...[more]