Ontology highlight
ABSTRACT:
SUBMITTER: Scarpa E
PROVIDER: S-EPMC6302072 | biostudies-literature | 2018 Dec
REPOSITORIES: biostudies-literature
Developmental cell 20181129 6
Cell shape is known to influence the plane of cell division. In vitro, mechanical constraints can also orient mitoses; however, in vivo it is not clear whether tension can orient the mitotic spindle directly, because tissue-scale forces can change cell shape. During segmentation of the Drosophila embryo, actomyosin is enriched along compartment boundaries forming supracellular cables that keep cells segregated into distinct compartments. Here, we show that these actomyosin cables orient the plan ...[more]