Ontology highlight
ABSTRACT:
SUBMITTER: Lee HN
PROVIDER: S-EPMC6303301 | biostudies-literature | 2018 Dec
REPOSITORIES: biostudies-literature
Lee Han-Na HN Shin Woo-Shik WS Seo Seung-Yeul SY Choi Si-Sun SS Song Ji-Soo JS Kim Ji-Yeon JY Park Ji-Hoon JH Lee Dohoon D Kim Sang Yong SY Lee Sang Joung SJ Chun Gie-Taek GT Kim Eung-Soo ES
Scientific reports 20181221 1
Muconic acid (MA) is a valuable compound for adipic acid production, which is a precursor for the synthesis of various polymers such as plastics, coatings, and nylons. Although MA biosynthesis has been previously reported in several bacteria, the engineered strains were not satisfactory owing to low MA titers. Here, we generated an engineered Corynebacterium cell factory to produce a high titer of MA through 3-dehydroshikimate (DHS) conversion to MA, with heterologous expression of foreign proto ...[more]