Ontology highlight
ABSTRACT:
SUBMITTER: Ogawa Y
PROVIDER: S-EPMC6304883 | biostudies-literature | 2018
REPOSITORIES: biostudies-literature
Ogawa Youichi Y Kinoshita Manao M Shimada Shinji S Kawamura Tatsuyoshi T
Journal of immunology research 20181209
In the skin, the epidermis is continuously exposed to various kinds of external substances and stimuli. Therefore, epidermal barriers are crucial for providing protection, safeguarding health, and regulating water balance by maintaining skin homeostasis. Disruption of the epidermal barrier allows external substances and stimuli to invade or stimulate the epidermal cells, leading to the elicitation of skin inflammation. The major components of the epidermal barrier are the stratum corneum (SC) an ...[more]