Circulating microRNAs as biomarkers for diabetic neuropathy: A novel approach.
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ABSTRACT:
SUBMITTER: Xourgia E
PROVIDER: S-EPMC6305524 | biostudies-literature | 2018 Nov
REPOSITORIES: biostudies-literature
Publications
Circulating microRNAs as biomarkers for diabetic neuropathy: A novel approach.
Xourgia Eleni E Papazafiropoulou Athanasia A Melidonis Andreas A
World journal of experimental medicine 20181130 3
Oxidative stress stemming from tissue exposure to constant hyperglycemia is one of the major pathogenetic pathways of diabetic macro- and microvascular complications. Diabetic polyneuropathy, commonly manifesting as distal, symmetrical sensorimotor polyneuropathy, is characterized by progressive severity of symptoms, with rates analogous to the quality of glycemic control achieved by the patients and physicians. Palliative care with analgesics and aggressive glycemic control often improve qualit ...[more]
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