Ontology highlight
ABSTRACT:
SUBMITTER: Koga S
PROVIDER: S-EPMC6309287 | biostudies-literature | 2018 Sep
REPOSITORIES: biostudies-literature
Koga Shunsuke S Kouri Naomi N Walton Ronald L RL Ebbert Mark T W MTW Josephs Keith A KA Litvan Irene I Graff-Radford Neill N Ahlskog J Eric JE Uitti Ryan J RJ van Gerpen Jay A JA Boeve Bradley F BF Parks Adam A Ross Owen A OA Dickson Dennis W DW
Acta neuropathologica 20180620 3
Corticobasal degeneration (CBD) is a clinically heterogeneous tauopathy, which has overlapping clinicopathologic and genetic characteristics with progressive supranuclear palsy (PSP). This study aimed to elucidate whether transactive response DNA-binding protein of 43 kDa (TDP-43) pathology contributes to clinicopathologic heterogeneity of CBD. Paraffin-embedded sections of the midbrain, pons, subthalamic nucleus, and basal forebrain from 187 autopsy-confirmed CBD cases were screened with immuno ...[more]