Ontology highlight
ABSTRACT:
SUBMITTER: Tutino VM
PROVIDER: S-EPMC6310942 | biostudies-literature | 2018 Dec
REPOSITORIES: biostudies-literature
Tutino Vincent M VM Poppenberg Kerry E KE Li Lu L Shallwani Hussain H Jiang Kaiyu K Jarvis James N JN Sun Yijun Y Snyder Kenneth V KV Levy Elad I EI Siddiqui Adnan H AH Kolega John J Meng Hui H
Journal of translational medicine 20181228 1
<h4>Background</h4>Intracranial aneurysms (IAs) are dangerous because of their potential to rupture and cause deadly subarachnoid hemorrhages. Previously, we found significant RNA expression differences in circulating neutrophils between patients with unruptured IAs and aneurysm-free controls. Searching for circulating biomarkers for unruptured IAs, we tested the feasibility of developing classification algorithms that use neutrophil RNA expression levels from blood samples to predict the presen ...[more]