Ontology highlight
ABSTRACT:
SUBMITTER: Denihan NM
PROVIDER: S-EPMC6311668 | biostudies-literature | 2019 Jan
REPOSITORIES: biostudies-literature
Denihan Niamh M NM Kirwan Jennifer A JA Walsh Brian H BH Dunn Warwick B WB Broadhurst David I DI Boylan Geraldine B GB Murray Deirdre M DM
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20170825 1
Elucidating metabolic effects of hypoxic-ischaemic encephalopathy (HIE) may reveal early biomarkers of injury and new treatment targets. This study uses untargeted metabolomics to examine early metabolic alterations in a carefully defined neonatal population. Infants with perinatal asphyxia who were resuscitated at birth and recovered (PA group), those who developed HIE (HIE group) and healthy controls were all recruited at birth. Metabolomic analysis of cord blood was performed using direct inf ...[more]