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Validity, reliability and minimum detectable change of COSMED K5 portable gas exchange system in breath-by-breath mode.


ABSTRACT:

Purpose

This study aimed to examine the validity, reliability and minimum detectable change (MDC) of the Cosmed K5 in breath by breath (BxB) mode, against VacuMed metabolic simulator. Intra and inter-units reliability was also assessed.

Methods

Fourteen metabolic rates (from 0.9 to 4 L.min-1) were reproduced by a VacuMed system and pulmonary ventilation (VE), oxygen consumption (VO2) and carbon dioxide production (VCO2) were measured by two different K5 units. Validity was assessed by ordinary least products (OLP) regression analysis, Bland-Altman plots, intraclass correlation coefficients (ICC), mean percentage differences, technical errors (TE) and MDC for VE, VO2, and VCO2. Intra- and inter-K5 reliability was evaluated by absolute percentage differences between measurements (MAPE), ICCs, TE, and MDC.

Results

Validity analysis from OLP regression data and Bland- Altman plots indicated high agreement between K5 and simulator. ICC values were excellent for all variables (>0.99). Mean percentage differences in VE (-0.50%, p = 0.11), VO2 (-0.04%, p = 0.80), and VCO2 (-1.03%, p = 0.09) showed no significant bias. The technical error (TE) ranged from 0.73% to 1.34% (VE and VCO2 respectively). MDC were lower than 4% (VE = 2.0%, VO2 = 3.8%, VCO2 = 3.7%). The intra and inter K5 reliability assessment reveled excellent ICCs (>0.99), MAPE <2% (no significant differences between trials), TE < or around 1%, MDC ConclusionsK5 in BxB mode is a valid and reliable system for metabolic measurements. This is the first study assessing the MDC accounting only for technical variability reporting intra- and inter-units MDCs <3.3%.

SUBMITTER: Guidetti L 

PROVIDER: S-EPMC6312326 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature

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Publications

Validity, reliability and minimum detectable change of COSMED K5 portable gas exchange system in breath-by-breath mode.

Guidetti Laura L   Meucci Marco M   Bolletta Francesco F   Emerenziani Gian Pietro GP   Gallotta Maria Chiara MC   Baldari Carlo C  

PloS one 20181231 12


<h4>Purpose</h4>This study aimed to examine the validity, reliability and minimum detectable change (MDC) of the Cosmed K5 in breath by breath (BxB) mode, against VacuMed metabolic simulator. Intra and inter-units reliability was also assessed.<h4>Methods</h4>Fourteen metabolic rates (from 0.9 to 4 L.min-1) were reproduced by a VacuMed system and pulmonary ventilation (VE), oxygen consumption (VO2) and carbon dioxide production (VCO2) were measured by two different K5 units. Validity was assesse  ...[more]

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