Ontology highlight
ABSTRACT:
SUBMITTER: Antwi-Boasiako C
PROVIDER: S-EPMC6313677 | biostudies-literature | 2018 Sep
REPOSITORIES: biostudies-literature
Antwi-Boasiako Charles C Dzudzor Bartholomew B Kudzi William W Doku Alfred A Dale Campbell Andrew CA Sey Fredericka F Otu Kate Hgar KH Boatemaa Gifty Dankwah GD Ekem Ivy I Ahenkorah John J Achel Daniel Gyingiri DG Aboagye Elvis Twumasi ET Donkor Eric S ES
Diseases (Basel, Switzerland) 20180929 4
Endothelial nitric oxide synthase (eNOS) variants have been found to be associated with several vascular disorders as well as the pathogenesis of sickle cell disease (SCD) complications such as vaso-occlusive crises (VOC). Studies on eNOS gene variants among SCD patients are rare in Ghana and several other African countries. The current study aimed to determine a possible association between variants of the eNOS gene (variable number of tandem repeats in intron 4 and T786C) in SCD complications ...[more]