Ontology highlight
ABSTRACT:
SUBMITTER: Bei C
PROVIDER: S-EPMC6313975 | biostudies-literature | 2018
REPOSITORIES: biostudies-literature
Bei Chunhua C Liu Shun S Yu Xiangyuan X Qiu Moqin M Tang Bo B Liao Weijia W He Songqing S Yu Hongping H
BioMed research international 20181219
Single nucleotide polymorphisms (SNPs) in microRNA may affect its expression and regulation of target genes, which may consequently alter individual susceptibility to cancer. In this study we aimed to investigate associations between <i>miR-122</i> polymorphisms and hepatocellular carcinoma (HCC) in a southern Chinese population. Three selected SNPs in <i>miR-122</i> (rs9966765, rs1135519, and rs17669) were genotyped in 1050 HCC patients and 1079 cancer-free controls using Sequenom MassARRAY pla ...[more]