Ontology highlight
ABSTRACT:
SUBMITTER: IMEx Consortium Curators
PROVIDER: S-EPMC6315030 | biostudies-literature | 2019 Jan
REPOSITORIES: biostudies-literature
Del-Toro N N Duesbury M M Koch M M Koch M M Perfetto L L Shrivastava A A Ochoa D D Wagih O O Piñero J J Kotlyar M M Pastrello C C Beltrao P P Furlong L I LI Jurisica I I Hermjakob H H Hermjakob H H Orchard S S Porras P P
Nature communications 20190102 1
The current wealth of genomic variation data identified at nucleotide level presents the challenge of understanding by which mechanisms amino acid variation affects cellular processes. These effects may manifest as distinct phenotypic differences between individuals or result in the development of disease. Physical interactions between molecules are the linking steps underlying most, if not all, cellular processes. Understanding the effects that sequence variation has on a molecule's interaction ...[more]