Ontology highlight
ABSTRACT:
SUBMITTER: Kossenkov AV
PROVIDER: S-EPMC6317999 | biostudies-literature | 2019 Jan
REPOSITORIES: biostudies-literature
Kossenkov Andrew V AV Qureshi Rehman R Dawany Noor B NB Wickramasinghe Jayamanna J Liu Qin Q Majumdar R Sonali RS Chang Celia C Widura Sandy S Kumar Trisha T Horng Wen-Hwai WH Konnisto Eric E Criner Gerard G Tsay Jun-Chieh J JJ Pass Harvey H Yendamuri Sai S Vachani Anil A Bauer Thomas T Nam Brian B Rom William N WN Showe Michael K MK Showe Louise C LC
Cancer research 20181128 1
Low-dose CT (LDCT) is widely accepted as the preferred method for detecting pulmonary nodules. However, the determination of whether a nodule is benign or malignant involves either repeated scans or invasive procedures that sample the lung tissue. Noninvasive methods to assess these nodules are needed to reduce unnecessary invasive tests. In this study, we have developed a pulmonary nodule classifier (PNC) using RNA from whole blood collected in RNA-stabilizing PAXgene tubes that addresses this ...[more]