Ontology highlight
ABSTRACT:
SUBMITTER: Pruneda JN
PROVIDER: S-EPMC6319605 | biostudies-literature | 2018 Dec
REPOSITORIES: biostudies-literature
Nature microbiology 20181105 12
Pathogenic bacteria are armed with potent effector proteins that subvert host signalling processes during infection<sup>1</sup>. The activities of bacterial effectors and their associated roles within the host cell are often poorly understood, particularly for Chlamydia trachomatis<sup>2</sup>, a World Health Organization designated neglected disease pathogen. We identify and explain remarkable dual Lys63-deubiquitinase (DUB) and Lys-acetyltransferase activities in the Chlamydia effector ChlaDUB ...[more]