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Effect of the soft-tissue techniques in the quality of life in patients with Crohn's disease: A randomized controlled trial.

ABSTRACT: BACKGROUND:Crohn's disease (CD) is a highly prevalent inflammatory bowel disease (IBD), characterized by recurring flares altered by periods of inactive disease and remission, affecting physical and psychological aspects and quality of life (QoL). The aim of this study was to determine the therapeutic benefits of soft non-manipulative osteopathic techniques in patients with CD. METHODS:A single-blind randomized controlled trial was performed. 30 individuals with CD were divided into 2 groups: 16 in the experimental group (EG) and 14 in the control group (CG). The intervention period lasted 30 days (1 session every 10 days). Pain, global quality of life (GQoL) and QoL specific for CD (QoLCD) were assessed before and after the intervention. Anxiety and depression levels were measured at the beginning of the study. RESULTS:We observed a significant effect of the treatment in both the physical and task subscales of the GQoL (P?=?.01 and P?=?.04, respectively) and also in the QoLCD (P??.0001) but not in pain score (P?=?.28). When the intensity of pain was taken into consideration in the analysis of the EG, there was a significantly greater increment in the QoLCD after treatment in people without pain than in those with pain (P?=?.02) The improvements in GQoL were independent from the disease status (P?=?.16). CONCLUSIONS:Soft, non-manipulative osteopathic treatment is effective in improving overall and physical-related QoL in CD patients, regardless of the phase of the disease. Pain is an important factor that inversely correlates with the improvements in QoL.

SUBMITTER: Espi-Lopez GV

PROVIDER: S-EPMC6320155 | biostudies-literature | 2018 Dec

REPOSITORIES: biostudies-literature

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Effect of the soft-tissue techniques in the quality of life in patients with Crohn's disease: A randomized controlled trial.

Espí-López Gemma V GV Inglés Marta M Soliva-Cazabán Isabel I Serra-Añó Pilar P

Medicine 20181201 51

<h4>Background</h4>Crohn's disease (CD) is a highly prevalent inflammatory bowel disease (IBD), characterized by recurring flares altered by periods of inactive disease and remission, affecting physical and psychological aspects and quality of life (QoL). The aim of this study was to determine the therapeutic benefits of soft non-manipulative osteopathic techniques in patients with CD.<h4>Methods</h4>A single-blind randomized controlled trial was performed. 30 individuals with CD were divided in ...[more]

PMID: 30572544

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Project description:Although partner violence screening has been endorsed by many health organizations, there is insufficient evidence that it has beneficial health outcomes.To determine the effect of computerized screening for partner violence plus provision of a partner violence resource list vs provision of a partner violence list only on women's health in primary care settings, compared with a control group.A 3-group blinded randomized controlled trial at 10 primary health care centers in Cook County, Illinois. Participants were enrolled from May 2009-April 2010 and reinterviewed 1 year (range, 48-56 weeks) later. Participants were English- or Spanish-speaking women meeting specific inclusion criteria and seeking clinical services at study sites. Of 3537 women approached, 2727 were eligible, 2708 were randomized (99%), and 2364 (87%) were recontacted 1 year later. Mean age of participants was 39 years. Participants were predominantly non-Latina African American (55%) or Latina (37%), had a high school education or less (57%), and were uninsured (57%).Randomization into 3 intervention groups: (1) partner violence screen (using the Partner Violence Screen instrument) plus a list of local partner violence resources if screening was positive (n = 909); (2) partner violence resource list only without screen (n = 893); and (3) no-screen, no-partner violence list control group (n=898).Quality of life (QOL, physical and mental health components) was the primary outcome, measured on the 12-item Short Form (scale range 0-100, mean of 50 for US population).At 1-year follow-up, there were no significant differences in the QOL physical health component between the screen plus partner violence resource list group (n = 801; mean score, 46.8; 95% CI, 46.1-47.4), the partner violence resource list only group (n = 772; mean score, 46.4; 95% CI, 45.8-47.1), and the control group (n = 791; mean score, 47.2; 95% CI, 46.5-47.8), or in the mental health component (screen plus partner violence resource list group [mean score, 48.3; 95% CI, 47.5-49.1], the partner violence resource list only group [mean score, 48.0; 95% CI, 47.2-48.9], and the control group [mean score, 47.8; 95% CI, 47.0-48.6]). There were also no differences between groups in days unable to work or complete housework; number of hospitalizations, emergency department, or ambulatory care visits; proportion who contacted a partner violence agency; or recurrence of partner violence.Among women receiving care in primary care clinics, providing a partner violence resource list with or without screening did not result in improved health.clinicaltrials.gov Identifier: NCT00526994.

Dataset Information

Effect of the soft-tissue techniques in the quality of life in patients with Crohn's disease: A randomized controlled trial.

Publications

Effect of the soft-tissue techniques in the quality of life in patients with Crohn's disease: A randomized controlled trial.

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