Dataset Information
Adolescent Medicine Trials Network for HIV/AIDS Interventions Data Harmonization: Rationale and Development of Guidelines.
Ontology highlight
ABSTRACT: Background
The Adolescent Medicine Trials Network for HIV/AIDS Interventions (ATN) research program aims to defeat the rising HIV epidemic among adolescents and young adults in the United States.Objective
This study aims to optimize cross-study analyses and comparisons of standardized measures (variables) collected in the ATN.Methods
Guidelines were developed for harmonizing measures to be collected across ATN studies.Results
Eight domains were identified for harmonization-Demographics and Socioeconomic Characteristics, Sexual Behavior and Risk, Substance Use and Abuse, HIV-Positive Cascade, HIV-Negative Cascade, Mental Health, Social Support and Isolation, and Pre-exposure Prophylaxis Cascade.Conclusions
The collection of selected key measures in a uniform manner across studies facilitates the characterization of participant populations, comparisons between studies, and pooled analysis of data from multiple studies.
SUBMITTER: McCumber M
PROVIDER: S-EPMC6320398 | biostudies-literature | 2018 Dec
REPOSITORIES: biostudies-literature
Publications
Adolescent Medicine Trials Network for HIV/AIDS Interventions Data Harmonization: Rationale and Development of Guidelines.
JMIR research protocols 20181221 12
<h4>Background</h4>The Adolescent Medicine Trials Network for HIV/AIDS Interventions (ATN) research program aims to defeat the rising HIV epidemic among adolescents and young adults in the United States.<h4>Objective</h4>This study aims to optimize cross-study analyses and comparisons of standardized measures (variables) collected in the ATN.<h4>Methods</h4>Guidelines were developed for harmonizing measures to be collected across ATN studies.<h4>Results</h4>Eight domains were identified for harm ...[more]