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Native Quercetin as a Chloride Receptor in an Organic Solvent.

ABSTRACT: The binding properties of quercetin toward chloride anions were investigated by means of ¹H-NMR, 13C-NMR, and electrospray ionization mass spectrometry (ESI-MS) measurements, as well as computational calculations. The results indicate that quercetin behaves primarily as a ditopic receptor with the binding site of the B ring that exhibits stronger chloride affinity compared to the A ring. However, these sites are stronger receptors than those of catechol and resorcinol because of their conjugation with the carbonyl group located on the C ring. The 1:1 and 1:2 complexation of this flavonoid with Cl- was also supported by ESI mass spectrometry.

SUBMITTER: Abdi Bellau ML

PROVIDER: S-EPMC6320934 | biostudies-literature | 2018 Dec

REPOSITORIES: biostudies-literature

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Native Quercetin as a Chloride Receptor in an Organic Solvent.

Abdi Bellau Mohamed Lamin ML Bortolini Olga O Fantin Giancarlo G Fogagnolo Marco M Ragno Daniele D Delso Ignacio I Merino Pedro P

Molecules (Basel, Switzerland) 20181219 12

The binding properties of quercetin toward chloride anions were investigated by means of ¹H-NMR, <sup>13</sup>C-NMR, and electrospray ionization mass spectrometry (ESI-MS) measurements, as well as computational calculations. The results indicate that quercetin behaves primarily as a ditopic receptor with the binding site of the B ring that exhibits stronger chloride affinity compared to the A ring. However, these sites are stronger receptors than those of catechol and resorcinol because of their ...[more]

PMID: 30572599

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Native Quercetin as a Chloride Receptor in an Organic Solvent.

Publications

Native Quercetin as a Chloride Receptor in an Organic Solvent.

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