Ontology highlight
ABSTRACT:
SUBMITTER: DebRoy S
PROVIDER: S-EPMC6321872 | biostudies-literature | 2018 Nov
REPOSITORIES: biostudies-literature
DebRoy Sruti S Li Xiqi X Kalia Awdhesh A Galloway-Pena Jessica J Shah Brittany J BJ Fowler Vance G VG Flores Anthony R AR Shelburne Samuel A SA
Microbial genomics 20181109 11
Group A Streptococcus (GAS) is classified on the basis of the sequence of the gene encoding the M protein (emm) and the patterns into which emm types are grouped. We discovered a novel emm pattern in emm4 GAS, historically considered pattern E, arising from a fusion event between emm and the adjacent enn gene. We identified the emm-enn fusion event in 51 out of 52 emm4 GAS strains isolated by national surveillance in 2015. GAS isolates with an emm-enn fusion event completely replaced pattern E e ...[more]