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Machine learning derived segmentation of phase velocity encoded cardiovascular magnetic resonance for fully automated aortic flow quantification.


ABSTRACT: BACKGROUND:Phase contrast (PC) cardiovascular magnetic resonance (CMR) is widely employed for flow quantification, but analysis typically requires time consuming manual segmentation which can require human correction. Advances in machine learning have markedly improved automated processing, but have yet to be applied to PC-CMR. This study tested a novel machine learning model for fully automated analysis of PC-CMR aortic flow. METHODS:A machine learning model was designed to track aortic valve borders based on neural network approaches. The model was trained in a derivation cohort encompassing 150 patients who underwent clinical PC-CMR then compared to manual and commercially-available automated segmentation in a prospective validation cohort. Further validation testing was performed in an external cohort acquired from a different site/CMR vendor. RESULTS:Among 190 coronary artery disease patients prospectively undergoing CMR on commercial scanners (84% 1.5T, 16% 3T), machine learning segmentation was uniformly successful, requiring no human intervention: Segmentation time was

SUBMITTER: Bratt A 

PROVIDER: S-EPMC6322266 | biostudies-literature | 2019 Jan

REPOSITORIES: biostudies-literature

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Machine learning derived segmentation of phase velocity encoded cardiovascular magnetic resonance for fully automated aortic flow quantification.

Bratt Alex A   Kim Jiwon J   Pollie Meridith M   Beecy Ashley N AN   Tehrani Nathan H NH   Codella Noel N   Perez-Johnston Rocio R   Palumbo Maria Chiara MC   Alakbarli Javid J   Colizza Wayne W   Drexler Ian R IR   Azevedo Clerio F CF   Kim Raymond J RJ   Devereux Richard B RB   Weinsaft Jonathan W JW  

Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance 20190107 1


<h4>Background</h4>Phase contrast (PC) cardiovascular magnetic resonance (CMR) is widely employed for flow quantification, but analysis typically requires time consuming manual segmentation which can require human correction. Advances in machine learning have markedly improved automated processing, but have yet to be applied to PC-CMR. This study tested a novel machine learning model for fully automated analysis of PC-CMR aortic flow.<h4>Methods</h4>A machine learning model was designed to track  ...[more]

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