Ontology highlight
ABSTRACT:
SUBMITTER: Ghosh D
PROVIDER: S-EPMC6325665 | biostudies-literature | 2019
REPOSITORIES: biostudies-literature
Cancer cell international 20190108
Genome editing allows for the precise manipulation of DNA sequences in a cell making this technology essential for understanding gene function. CRISPR/Cas9 is a targeted genome-editing platform derived from bacterial adaptive immune system and has been repurposed into a genome-editing tool. The RNA-guided DNA endonuclease, Cas9 can be easily programmed to target new sites by altering its guide RNA sequence, making this technology easier, more efficient, scalable and an indispensable tool in biol ...[more]