Ontology highlight
ABSTRACT:
SUBMITTER: Hwang MT
PROVIDER: S-EPMC6326894 | biostudies-literature | 2018 Jul
REPOSITORIES: biostudies-literature
Advanced materials (Deerfield Beach, Fla.) 20180709
Electronic DNA-biosensor with a single nucleotide resolution capability is highly desirable for personalized medicine. However, existing DNA-biosensors, especially single nucleotide polymorphism (SNP) detection systems, have poor sensitivity and specificity and lack real-time wireless data transmission. DNA-tweezers with graphene field effect transistor (FET) are used for SNP detection and data are transmitted wirelessly for analysis. Picomolar sensitivity of quantitative SNP detection is achiev ...[more]