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High-Depth RNA-Seq Data Sets for Studying Gene Expression Changes Mediated by Phase-Variable DNA Methyltransferases in Nontypeable Haemophilus influenzae.

ABSTRACT: Nontypeable Haemophilus influenzae (NTHi) is a major bacterial pathogen that causes multiple infections. We report high-depth-coverage RNA-Seq data from three NTHi strains, each of which encodes a different phase-variable methyltransferase. Major gene expression differences occur, commensurate with modA phase variation, and data will serve as an important resource for future studies.

SUBMITTER: Atack JM

PROVIDER: S-EPMC6328670 | biostudies-literature | 2019 Jan

REPOSITORIES: biostudies-literature

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High-Depth RNA-Seq Data Sets for Studying Gene Expression Changes Mediated by Phase-Variable DNA Methyltransferases in Nontypeable Haemophilus influenzae.

Atack John M JM Bakaletz Lauren O LO Jennings Michael P MP

Microbiology resource announcements 20190110 2

Nontypeable Haemophilus influenzae (NTHi) is a major bacterial pathogen that causes multiple infections. We report high-depth-coverage RNA-Seq data from three NTHi strains, each of which encodes a different phase-variable methyltransferase. Major gene expression differences occur, commensurate with <i>modA</i> phase variation, and data will serve as an important resource for future studies. ...[more]

PMID: 30643897

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