Ontology highlight
ABSTRACT:
SUBMITTER: Guo K
PROVIDER: S-EPMC6331448 | biostudies-literature | 2018
REPOSITORIES: biostudies-literature
Guo Kangkang K Xu Lei L Wu Mengmeng M Hou Yufeng Y Jiang Yanfen Y Lv Jiangman J Xu Panpan P Fan Zhixin Z Zhang Ruiqi R Xing Fushan F Zhang Yanming Y
Frontiers in microbiology 20190108
Porcine circovirus type 2 (PCV2) is the infectious agent of postweaning multisystemic wasting syndrome (PMWS). The recently discovered open reading frame 5 (ORF5) in PCV2 genome encodes a non-structural protein. Previous study revealed that ORF5 protein inhibits cell proliferation and may interact with host transmembrane glycoprotein NMB (GPNMB). However, whether the GPNMB affects PCV2 replication and the underlying molecular mechanisms are still unknown. In this study, the transcriptome maps of ...[more]