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Spectral contrast optical coherence tomography angiography enables single-scan vessel imaging.


ABSTRACT: Optical coherence tomography angiography relies on motion for contrast and requires at least two data acquisitions per pointwise scanning location. We present a method termed spectral contrast optical coherence tomography angiography using visible light that relies on the spectral signatures of blood for angiography from a single scan using endogenous contrast. We demonstrate the molecular sensitivity of this method, which enables lymphatic vessel, blood, and tissue discrimination.

SUBMITTER: Winkelmann JA 

PROVIDER: S-EPMC6333625 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature

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Spectral contrast optical coherence tomography angiography enables single-scan vessel imaging.

Winkelmann James A JA   Eid Aya A   Spicer Graham G   Almassalha Luay M LM   Nguyen The-Quyen TQ   Backman Vadim V  

Light, science & applications 20190116


Optical coherence tomography angiography relies on motion for contrast and requires at least two data acquisitions per pointwise scanning location. We present a method termed spectral contrast optical coherence tomography angiography using visible light that relies on the spectral signatures of blood for angiography from a single scan using endogenous contrast. We demonstrate the molecular sensitivity of this method, which enables lymphatic vessel, blood, and tissue discrimination. ...[more]

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