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Trends in incidence and survival of esophageal cancer in Korea: Analysis of the Korea Central Cancer Registry Database.


ABSTRACT: BACKGROUND AND AIM:The diagnostic and therapeutic modalities of esophageal cancer have recently improved in Asia, and its prognosis is expected to change. This study provides a population-based report on the epidemiology of esophageal cancer in Korea. METHODS:Cancer incidence data from 1999 to 2013 were obtained from the Korea Central Cancer Registry, covering the entire population. Age-standardized incidence rates and annual percent changes were calculated according to subsites and histological types. Five-year relative survival rates were estimated for cases diagnosed between 1993 and 2013. Relative excess rates were compared between patients diagnosed from 2009 to 2013 and 2006 to 2008. RESULTS:The age-standardized incidence rates decreased from 8.8 per 100 000 populations in 1999 to 5.9 in 2013 with an annual percent change of -2.6% in men and -2.2% in women. The most common histological type was squamous cell carcinoma, accounting for 90.2% of all esophageal cancers in 2013, followed by adenocarcinomas (3.1%), and their incidences decreased. The proportion of localized and regional cancer tended to increase compared with that of distant cancer. Five-year relative survival of squamous cell carcinoma improved from 12.1% (1993-1995) to 34.6% (2009-2013). Relative excess rate was 0.72 (95% confidence interval 0.65-0.80) in localized stage and 0.88 (95% confidence interval, 0.82-0.95) in regional stage comparing patients diagnosed from 2009 to 2013 and 2006 to 2008. CONCLUSIONS:The incidence of esophageal cancer has decreased in Korea for the past 15 years, and 5-year survival rates have improved significantly. These increases may be attributable to more effective detection of early-stage disease.

SUBMITTER: Shin A 

PROVIDER: S-EPMC6334276 | biostudies-literature | 2018 Dec

REPOSITORIES: biostudies-literature

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Trends in incidence and survival of esophageal cancer in Korea: Analysis of the Korea Central Cancer Registry Database.

Shin Aesun A   Won Young-Joo YJ   Jung Hye-Kyung HK   Kong Hyun-Joo HJ   Jung Kyu-Won KW   Oh Chang-Mo CM   Choe Sunho S   Lee Jihyun J  

Journal of gastroenterology and hepatology 20180612 12


<h4>Background and aim</h4>The diagnostic and therapeutic modalities of esophageal cancer have recently improved in Asia, and its prognosis is expected to change. This study provides a population-based report on the epidemiology of esophageal cancer in Korea.<h4>Methods</h4>Cancer incidence data from 1999 to 2013 were obtained from the Korea Central Cancer Registry, covering the entire population. Age-standardized incidence rates and annual percent changes were calculated according to subsites a  ...[more]

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